MiR‐492 impairs the angiogenic potential of endothelial cells
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چکیده
منابع مشابه
MiR-492 impairs the angiogenic potential of endothelial cells
Endothelial cells growing in high glucose-containing medium show reduced cell proliferation and in vitro angiogenesis. Evidence suggests that the molecular pathways leading to these cellular responses are controlled by microRNAs, endogenous post-transcriptional regulators of gene expression. To identify the microRNAs and their targeted genes involved in the glucose responses, we performed the m...
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Age-related impairment of angiogenesis is likely to play a central role in cerebromicrovascular rarefaction and development of vascular cognitive impairment, but the underlying mechanisms remain elusive. To test the hypothesis that dysregulation of Dicer1 (ribonuclease III, a key enzyme of the microRNA [miRNA] machinery) impairs endothelial angiogenic capacity in aging, primary cerebromicrovasc...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2013
ISSN: 1582-1838,1582-4934
DOI: 10.1111/jcmm.12085